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MCQ Test: Radiotherapy & chemotherapy


 Number of questions in this MCQ test: 9
Suggested time for this MCQ test: 11 minutes
  1. A chemotherapeutic agent that causes the persistent aggregation of microtubules is ?
    Cisplatin
    Paclitaxel (Taxol)
    Vincristine
    Bleomycin
    Vinblastine

  2. Methotrexate, a drug commonly used in the treatment of patients with malignant gestational trophoblastic disease and the medical treatment of ectopic pregnancy acts by being a(n) ?
    Alkylating agent
    Antitumor antibiotic
    Toposisomerase inhibitor
    Antimetabolite
    Spindel poison

  3. All of the following chemotherapeutic agents bond to the DNA of the tumor cell except ?
    Cisplatin
    Cyclophosphamide
    Carboplatinum
    Ifosfamide
    Vincristine

  4. All of the following are true about intracavitary radiotherapy except ?
    Follows the inverse square law
    Often uses 137Cs (cesium) or 226Ra (radium) in the treatment of cervical cancer.
    In the treatment of cervical cancer, uses an intrauterine tandem and vaginal ovoids.
    Usually given before external beam, treatment has been started.
    In cervical cancer specific reference points are used to specify the treatment prescription.

  5. A patient is receiving primary radiotherapy for a stage IIB cervical cancer. During the course of the external beam radiotherapy, the patient also receives concomitant chemotherapy. All of the following apply to such a use of chemotherapy except ?
    Cisplatin is commonly used in such a clinical setting
    The chemotherapeutic agent is used to achieve maximum cell killing, in the same way it is used without radiation.
    The radiation dosages used are essentially the same as those used without the chemotherapy.
    Chemotherapeutic agent is given to act as a radiation sensitizer.
    Use of such chemotherapy in addition to radiotherapy produces superior results as compared to radiation alone

  6. A cell-specific agent causing alopecia and significant risk of allergic reaction is ?
    Cyclophosphamide
    Paclitaxel (Taxol)
    Vincristine
    Methotrexate
    Carboplatinum

  7. A chemotherapeutic agent which largely causes its cytotoxic effect during the S- phase of the cell cycle is ?
    Carboplatinum
    Methotrexate
    Cyclophosphamide
    Taxol
    Doxorubicin (Andriamycin)

  8. An intravenously administered, cell-cycle independent agent commonly used in the treatment of gestational trophoblastic disease is ?
    Methotrexate
    Vincristine
    Paclitaxel (Taxol)
    Actinomycin D
    Doxorubicin (Andrianmycin)

  9. A class of chemotherapeutic agents associated with an increased risk of premature ovarian failure and a second malignancy ?
    Alkylating agent
    Antitumor antibiotic
    Antimetabolites
    Plant alkaloids in general
    Taxanes (Paclitaxel/Docetaxel)

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