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ExamPro MCQ Tests

MCQ Test: Ovarian cancer

Number of questions in this MCQ test: 8
Suggested time for this MCQ test: 10 minutes

A patients undergoes TAH, BSO for a pelvic mass. The pelvic mass is composed of a 7 cm lesion within the right ovary. A frozen section demonstrates Call-Exner bodies. What additional pathology is most likely to be demonstrated ?
An ovarian epithelial carcinoma
A Brenner cell tumor of the ovary
Endometrial carcinoma
Clear cell carcinoma of the cervix
A fallopian tube cancer
CA-125 is ?
A mucin-type glycoprtein
A ganglioside
A tumor-specific transplantation antigen
Useful for ovarian cancer screening in the general patient population
An antigen which is commonly expressed by mucinous ovarian carcinomas
A 50 year-old patient is found to have a stage IA, well differentiated ovarian epithelial cancer. The patient should then ?
Be closely followed without further treatment
Receive oral melphalan
Receive three cycles of Paclitaxel and Carboplatinum
Receive six cycles of Paclitaxel and Carboplatinum
Receive six cycles of Paclitaxel and Cisplatin
A patients undergoes staging surgery for a pelvic mas. She is found to have a stage III-C, suboptimally debulked, ovarian epithelial cancer. The best chemotherapy for this woman would consist of ?
bleomycin and cisplatinum
Paclitaxel
Paclitaxel and carboplatinum given intravenously
Paclitaxel and cisplatinum given intraperitoneally
cyclophosphamide and cisplatinum
An 18 year-old woman is found to have a largely solid ovarian neoplasm. Tumor markers were obtained and demonstrated a markedly elevated LDH value. The hCG and a-Fetoprotein were negative. Which of the following tumors is the most likely histology for this neoplasm ?
Dysgerminoma
endodermal sinus tumor
choriocarcincoma
immature teratoma
gonadoblastoma
What percentage of ovarian epithelial cancers occur on a hereditary basis ?
5 to 10%
20 to 30%
40 to 50%
60 to 70%
75 to 85%
The majority of ovarian epithelial cancers occurring on a hereditary basis arise in individuals with germline mutations in which gene ?
p53
BRCA 1
BRCA 2
MSH 2 (One of the genes causing hereditary nonpolyposis colorectal cancer)
Retinoblastoma protein
Prophylactic "oophorectomy" in patient with BRCA 1 mutations implies or results in the following ?
Reduces the risk of breast cancer
Necessitates removal of fallopian tubes
Peritoneal cytologies should be done at the time of prophylactic oophrectomy
Patients can still develop intra-abdominal papillary serious cancers as a result of primary peritoneal cancers
All of the above

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