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MCQ Test: Endometrial Neoplasia


Number of questions in this MCQ test: 6
Suggested time for this MCQ test: 7
minutes
  1. The most important predictor of the behavior of an endometrial hyperplasia is:
    Patient age
    Presence of atypia
    Complex vs. simple hyperplasia
    Hormone (estrogen) receptor status of tissue obtained at curettage
    Presence of aneuploidy

  2. In patients with complex atypical endometrial hyperplasia by endometrial biopsy or curettage, what percentage will actually have endometrail cancer at hystectomy?
    < 1%
    < 5%
    < 10%
    < 15 %
    > 25%

  3. A 29-year-old woman is found to have an endometrial cancer. All of the following would be expected, with the EXCEPTION of:
    The patient probably has chronic anovulation and may have polycystic ovarian syndrome
    The tumor is well differentiated and is non-invasive or superficially invasive into the myometrium
    May potentially be treated with the use of progestins
    A pelvic ultrasound would be beneficial to rule out a synchronous ovarian neoplasm
    Probably has a tumor with nonendometrioid histology

  4. Which of the following is false in regard to non-endometrioid adenocarcinomas of the uterus?
    Non-endometrioid adenocarcinomas constitute about 10% of endometrial cancers
    Are biologically more aggressive than the traditional endometrioid adenocarcinoma
    Can demonstrate clear cell and papillary serous histologies
    In the absence of adnexal involvement, these tumors do not have an adverse prognosis
    Are staged in the same manner as endometrioid adenocarcinomas

  5. All of the following are true about tamoxifen and raloxifen in regards to endometrial neoplasia EXCEPT :
    Tamoxifen increases the risk endometrial cancers twofold to threefold
    An annual endometrial biopsy in asymptomatic patients on tamoxifen is not necessary
    Tamoxifen and raloxifen are selective estrogen receptor modulators
    Raloxifen increases the risk of endometrial hyperplasia and adenocarcinomas
    Tamoxifen administration increases the thickness of the endometrail stripe; Routine ultrasound surveillance in asymptomatic patients on taxoxifen is not useful

  6. Which of the following are true in regards to uterine sarcomas?
    Although saecomas account for only 3% of uterine cancers, they often have a poor prognosis
    Leiomyosarcomas usually arise de novo from the uterine smooth muscle, rather than from a preexisting fibroid
    Rapid enlargement of a presumed fibroid uterus is a potential sign of a leiomyosarcoma
    There is no offical staging system for uterine sarcomas, but it is customary to use the FIGO system for endometrial cancers
    All of the above are true

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