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MCQ Test: Breast Disease


Number of questions in this MCQ test: 8
Suggested time for this MCQ test: 10
  1. The most frequent location of breast cancer is ?
    Upper outer quadrant
    Upper inner quadrant
    Lower outer quadrant
    Lower inner quadrant
    Subareolar location

  2. All of the following statements about ductal carcinoma in situ are true except?
    Typically occurs in premenopausal women
    May appear as a palpable mass or a mammographic abnormality
    Associated with an increased risk of invasive breast cancer in the affected breast
    May be treated with lumpectomy and radiotherapy
    May be treated with total mastectomy

  3. Which of the following are true about the use of tamoxifen trial in the prevention of breast cancer as sponsored by the NSABP?
    Tamoxifen or placebo was given to women with an increased risk of breast cancer
    Use of tamoxifen was associated with increased risk of cataracts, strokes and pulmonary emboli
    Use of tamoxifen reduced the risk of in situ breast carcinoma
    Use of tamoxifen reduced the risk of breast cancer by reducing the incidence of tumors that were estrogen receptor positive
    All of the above

  4. Which of the following is the most important prognostic factor in the survival of patients with breast cancer?
    Tumor size
    Hormone receptor status
    Status of the axillary lymph nodes
    Patient age
    Overexpression of Her-2-neu

  5. Most frequent cause of bloody nipple discharge without an associated mass by examination?
    Ductal ectasia
    Intraductal papilloma
    Breast cancer
    Ductal carcinoma in situ
    Phylloides tumor

  6. A 24 year old woman presents with an isolated 1.5 cm breast mass. The nature of the mass is unclear at the time of examination. Which of the following is the most reasonable next step ?
    Mammography
    MRI
    Ultrasound of the mass
    Open biopsy
    Mammotome Biopsy

  7. Which of the following statements are not true about breast cancer in patients with BRCA germline mutations?
    Most breast cancers in BRCA1 patients are estrogen receptor (ER) positive
    At least 50% arise in women less than the age of 50
    Prophylactic adnexectomy reduces the risk of breast cancer
    BRCA 1 and BRCA 1 germline mutations account for most hereditary breast cancers
    Prophylactic mastectmoy diminishes the risk of breast cancer in patients with BRCA 1 and 2 germline mutations

  8. A marker of increased risk of invasive breast cancer in either breast?
    Ductal carcinoma in situ
    Paget's disease
    Lobular carcinoma in situ
    Ductal ectasia
    Intraductal papilloma

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